In silico identification of rescue sites by double force scanning

MOTIVATION: A deleterious amino acid change in a protein can be compensated by a second-site rescue mutation. These compensatory mechanisms can be mimicked by drugs. In particular, the location of rescue mutations can be used to identify protein regions that can be targeted by small molecules to rea...

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Detalles Bibliográficos
Autores principales: Tiberti, Matteo, Pandini, Alessandro, Fraternali, Franca, Fornili, Arianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860198/
https://www.ncbi.nlm.nih.gov/pubmed/28961796
http://dx.doi.org/10.1093/bioinformatics/btx515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860198/
https://www.ncbi.nlm.nih.gov/pubmed/28961796
http://dx.doi.org/10.1093/bioinformatics/btx515

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