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Identifying simultaneous rearrangements in cancer genomes
MOTIVATION: The traditional view of cancer evolution states that a cancer genome accumulates a sequential ordering of mutations over a long period of time. However, in recent years it has been suggested that a cancer genome may instead undergo a one-time catastrophic event, such as chromothripsis, w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860217/ https://www.ncbi.nlm.nih.gov/pubmed/29186385 http://dx.doi.org/10.1093/bioinformatics/btx745 |