Genome-scale regression analysis reveals a linear relationship for promoters and enhancers after combinatorial drug treatment

MOTIVATION: Drug combination therapy for treatment of cancers and other multifactorial diseases has the potential of increasing the therapeutic effect, while reducing the likelihood of drug resistance. In order to reduce time and cost spent in comprehensive screens, methods are needed which can mode...

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Detalles Bibliográficos
Autores principales: Rapakoulia, Trisevgeni, Gao, Xin, Huang, Yi, de Hoon, Michiel, Okada-Hatakeyama, Mariko, Suzuki, Harukazu, Arner, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Discovery Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860321/
https://www.ncbi.nlm.nih.gov/pubmed/28961713
http://dx.doi.org/10.1093/bioinformatics/btx503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860321/
https://www.ncbi.nlm.nih.gov/pubmed/28961713
http://dx.doi.org/10.1093/bioinformatics/btx503

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