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Genome-scale regression analysis reveals a linear relationship for promoters and enhancers after combinatorial drug treatment
MOTIVATION: Drug combination therapy for treatment of cancers and other multifactorial diseases has the potential of increasing the therapeutic effect, while reducing the likelihood of drug resistance. In order to reduce time and cost spent in comprehensive screens, methods are needed which can mode...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860321/ https://www.ncbi.nlm.nih.gov/pubmed/28961713 http://dx.doi.org/10.1093/bioinformatics/btx503 |