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Correcting the Standard Errors of 2-Stage Residual Inclusion Estimators for Mendelian Randomization Studies

Mendelian randomization studies use genotypes as instrumental variables to test for and estimate the causal effects of modifiable risk factors on outcomes. Two-stage residual inclusion (TSRI) estimators have been used when researchers are willing to make parametric assumptions. However, researchers...

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Detalles Bibliográficos
Autores principales: Palmer, Tom M, Holmes, Michael V, Keating, Brendan J, Sheehan, Nuala A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860380/
https://www.ncbi.nlm.nih.gov/pubmed/29106476
http://dx.doi.org/10.1093/aje/kwx175