Feature selection using a one dimensional naïve Bayes’ classifier increases the accuracy of support vector machine classification of CDR3 repertoires

MOTIVATION: Somatic DNA recombination, the hallmark of vertebrate adaptive immunity, has the potential to generate a vast diversity of antigen receptor sequences. How this diversity captures antigen specificity remains incompletely understood. In this study we use high throughput sequencing to compa...

Descripción completa

Detalles Bibliográficos
Autores principales: Cinelli, Mattia, Sun, , Yuxin, Best, Katharine, Heather, James M, Reich-Zeliger, Shlomit, Shifrut, Eric, Friedman, Nir, Shawe-Taylor, John, Chain, Benny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Discovery Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860388/
https://www.ncbi.nlm.nih.gov/pubmed/28073756
http://dx.doi.org/10.1093/bioinformatics/btw771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860388/
https://www.ncbi.nlm.nih.gov/pubmed/28073756
http://dx.doi.org/10.1093/bioinformatics/btw771

Ejemplares similares