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AnglerFish: a webserver for defining the geometry of α-helices in membrane proteins

SUMMARY: Integral membrane proteins that form helical pores and bundles constitute major drug targets, and many of their structures have been defined by crystallography and cryo-electron microscopy. The gating of channels and ligand binding of transporters generally involve changes in orientation of...

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Detalles Bibliográficos
Autores principales: Colledge, Matthew, Wallace, B A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860525/
https://www.ncbi.nlm.nih.gov/pubmed/28035031
http://dx.doi.org/10.1093/bioinformatics/btw781