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DIEGO: detection of differential alternative splicing using Aitchison’s geometry

MOTIVATION: Alternative splicing is a biological process of fundamental importance in most eukaryotes. It plays a pivotal role in cell differentiation and gene regulation and has been associated with a number of different diseases. The widespread availability of RNA-Sequencing capacities allows an e...

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Detalles Bibliográficos
Autores principales: Doose, Gero, Bernhart, Stephan H, Wagener, Rabea, Hoffmann, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860559/
https://www.ncbi.nlm.nih.gov/pubmed/29088309
http://dx.doi.org/10.1093/bioinformatics/btx690