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DIEGO: detection of differential alternative splicing using Aitchison’s geometry
MOTIVATION: Alternative splicing is a biological process of fundamental importance in most eukaryotes. It plays a pivotal role in cell differentiation and gene regulation and has been associated with a number of different diseases. The widespread availability of RNA-Sequencing capacities allows an e...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860559/ https://www.ncbi.nlm.nih.gov/pubmed/29088309 http://dx.doi.org/10.1093/bioinformatics/btx690 |