Cargando…

Ursolic acid rich Ocimum sanctum L leaf extract loaded nanostructured lipid carriers ameliorate adjuvant induced arthritis in rats by inhibition of COX-1, COX-2, TNF-α and IL-1: Pharmacological and docking studies

BACKGROUND: Ursolic acid (UA) is a promising molecule with anti-inflammatory, analgesic and potential anti-arthritic activity. METHODS: This study was undertaken to make formulation and evaluation of Ocimum sanctum L. leaf extract (OLE) loaded nano-structured lipid carriers (OLE-NLCs) for improved t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmad, Aftab, Abuzinadah, Mohammed F., Alkreathy, Huda M., Banaganapalli, Babajan, Mujeeb, Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860693/
https://www.ncbi.nlm.nih.gov/pubmed/29558494
http://dx.doi.org/10.1371/journal.pone.0193451