Exercise Prevents Maternal High-Fat Diet–Induced Hypermethylation of the Pgc-1α Gene and Age-Dependent Metabolic Dysfunction in the Offspring

Abnormal conditions during early development adversely affect later health. We investigated whether maternal exercise could protect offspring from adverse effects of a maternal high-fat diet (HFD) with a focus on the metabolic outcomes and epigenetic regulation of the metabolic master regulator, per...

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Detalles Bibliográficos
Autores principales: Laker, Rhianna C., Lillard, Travis S., Okutsu, Mitsuharu, Zhang, Mei, Hoehn, Kyle L., Connelly, Jessica J., Yan, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860829/
https://www.ncbi.nlm.nih.gov/pubmed/24430439
http://dx.doi.org/10.2337/db13-1614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860829/
https://www.ncbi.nlm.nih.gov/pubmed/24430439
http://dx.doi.org/10.2337/db13-1614

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