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Characterization of a murine model of non-lethal, symptomatic dengue virus infection

The mosquito-borne disease dengue is caused by four serologically- and genetically-related viruses, termed DENV-1 to DENV-4. Historical setbacks due to lack of human-like mouse models of dengue were partially remedied with characterization of lethal DENV-2 infection in immunocompromised AG129 mice (...

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Detalles Bibliográficos
Autores principales: Sarathy, Vanessa V., White, Mellodee, Li, Li, Kaiser, Jaclyn A., Campbell, Gerald A., Milligan, Gregg N., Bourne, Nigel, Barrett, Alan D. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861036/
https://www.ncbi.nlm.nih.gov/pubmed/29559699
http://dx.doi.org/10.1038/s41598-018-22618-w