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Redefining the ancestral origins of the interleukin-1 superfamily

The interleukin-1 (IL-1) receptor and ligand families are components of the immune system. Knowledge of their evolutionary history is essential to understand their function. Using chromosomal anatomy and sequence similarity, we show that IL-1 receptor family members are related and nine members are...

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Detalles Bibliográficos
Autores principales: Rivers-Auty, Jack, Daniels, Michael J. D., Colliver, Isaac, Robertson, David L., Brough, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861070/
https://www.ncbi.nlm.nih.gov/pubmed/29559685
http://dx.doi.org/10.1038/s41467-018-03362-1