IL-3R-alpha blockade inhibits tumor endothelial cell-derived extracellular vesicle (EV)-mediated vessel formation by targeting the β-catenin pathway

The proangiogenic cytokine Interleukin-3 (IL-3) is released by inflammatory cells in breast and ovarian cancer tissue microenvironments and also acts as an autocrine factor for human breast and kidney tumor-derived endothelial cells (TECs). We have previously shown that IL-3-treated endothelial cell...

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Detalles Bibliográficos
Autores principales: Lombardo, Giusy, Gili, Maddalena, Grange, Cristina, Cavallari, Claudia, Dentelli, Patrizia, Togliatto, Gabriele, Taverna, Daniela, Camussi, Giovanni, Brizzi, Maria Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861089/
https://www.ncbi.nlm.nih.gov/pubmed/29238040
http://dx.doi.org/10.1038/s41388-017-0034-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861089/
https://www.ncbi.nlm.nih.gov/pubmed/29238040
http://dx.doi.org/10.1038/s41388-017-0034-x

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