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SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis

Slit-Robo GTPase-activating protein 1 (SRGAP1) functions as a GAP for Rho-family GTPases and downstream of Slit-Robo signaling. We aim to investigate the biological function of SRGAP1 and reveal its regulation by deregulated microRNAs (miRNAs) in gastric cancer (GC). mRNA and protein expression of S...

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Detalles Bibliográficos
Autores principales: Huang, Tingting, Zhou, Yuhang, Zhang, Jinglin, Wong, Chi Chun, Li, Weilin, Kwan, Johnny S. H., Yang, Rui, Chan, Aden K. Y., Dong, Yujuan, Wu, Feng, Zhang, Bin, Cheung, Alvin H. K., Wu, William K. K., Cheng, Alfred S. L., Yu, Jun, Wong, Nathalie, Kang, Wei, To, Ka Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861093/
https://www.ncbi.nlm.nih.gov/pubmed/29234151
http://dx.doi.org/10.1038/s41388-017-0029-7