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Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex

The NuA4/TIP60 acetyltransferase complex is required for gene regulation, DNA repair and cell cycle progression. The limited structural information impeded understanding of NuA4/TIP60 assembly and regulatory mechanism. Here, we report the 4.7 Å cryo-electron microscopy (cryo-EM) structure of a NuA4/...

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Detalles Bibliográficos
Autores principales: Wang, Xuejuan, Ahmad, Salar, Zhang, Zhihui, Côté, Jacques, Cai, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861120/
https://www.ncbi.nlm.nih.gov/pubmed/29559617
http://dx.doi.org/10.1038/s41467-018-03504-5