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Suppressor of cytokine signalling-2 limits IGF1R-mediated regulation of epithelial–mesenchymal transition in lung adenocarcinoma

Non-small cell lung cancer (NSCLC), including adenocarcinoma and squamous cell carcinoma, is the leading cause of death from lung malignancies and has a poor prognosis due to metastasis. Suppressor of cytokine signalling-2 (SOCS2), a feedback inhibitor of cytokine signalling, has been shown to be in...

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Detalles Bibliográficos
Autores principales: Zhou, Yue, Zhang, Zhilei, Wang, Ning, Chen, Jizheng, Zhang, Xu, Guo, Min, John Zhong, Li, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861121/
https://www.ncbi.nlm.nih.gov/pubmed/29559623
http://dx.doi.org/10.1038/s41419-018-0457-5