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Quantifying the impact of simple DNA parameters on the cyclization J-factor for single-basepair-addition families

We use Monte Carlo simulation to quantify the change in cyclization J-factor within a dramatically simplified model of DNA that involves parameters for uniform stiffnesses, intrinsic twist, and intrinsic bending (including nonplanar bending). Plots of J versus DNA length over multiple periods of hel...

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Detalles Bibliográficos
Autores principales: Tong, Yunjin, Manning, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861124/
https://www.ncbi.nlm.nih.gov/pubmed/29559729
http://dx.doi.org/10.1038/s41598-018-22502-7