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Quantifying the impact of simple DNA parameters on the cyclization J-factor for single-basepair-addition families
We use Monte Carlo simulation to quantify the change in cyclization J-factor within a dramatically simplified model of DNA that involves parameters for uniform stiffnesses, intrinsic twist, and intrinsic bending (including nonplanar bending). Plots of J versus DNA length over multiple periods of hel...
Autores principales: | Tong, Yunjin, Manning, Robert S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861124/ https://www.ncbi.nlm.nih.gov/pubmed/29559729 http://dx.doi.org/10.1038/s41598-018-22502-7 |
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