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Identification of new inhibitors against human Great wall kinase using in silico approaches

Microtubule associated serine/threonine kinase (MASTL) is an important Ser/Thr kinase belonging to the family of AGC kinases. It is the human orthologue of Greatwall kinase (Gwl) that plays a significant role in mitotic progression and cell cycle regulation. Upregulation of MASTL in various cancers...

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Detalles Bibliográficos
Autores principales: Ammarah, Ummi, Kumar, Amit, Pal, Rajesh, Bal, Naresh C., Misra, Gauri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861128/
https://www.ncbi.nlm.nih.gov/pubmed/29559668
http://dx.doi.org/10.1038/s41598-018-23246-0