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Complement C1q stimulates the progression of hepatocellular tumor through the activation of discoidin domain receptor 1

C1q is known to perform several functions in addition to the role it plays in complement activation. C1q contains a collagen-like portion and DDR1 (discoidin domain receptor 1) is a well-known collagen receptor. Accordingly, we hypothesized C1q might be a novel ligand of DDR1. This study shows for t...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Hyun, Poudel, Barun, Ki, Hyeon-Hui, Nepali, Sarmila, Lee, Young-Mi, Shin, Jeon-Soo, Kim, Dae-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861131/
https://www.ncbi.nlm.nih.gov/pubmed/29559654
http://dx.doi.org/10.1038/s41598-018-23240-6