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Whole-Inactivated Influenza Virus Is a Potent Adjuvant for Influenza Peptides Containing CD8(+) T Cell Epitopes

Influenza peptide antigens coding for conserved T cell epitopes have the capacity to induce cross-protective influenza-specific immunity. Short peptide antigens used as a vaccine, however, often show poor immunogenicity. In this study, we demonstrate that whole-inactivated influenza virus (WIV) acts...

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Detalles Bibliográficos
Autores principales: Soema, Peter C., Rosendahl Huber, Sietske K., Willems, Geert-Jan, Jacobi, Ronald, Hendriks, Marion, Soethout, Ernst, Jiskoot, Wim, de Jonge, Jørgen, van Beek, Josine, Kersten, Gideon F. A., Amorij, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861146/
https://www.ncbi.nlm.nih.gov/pubmed/29593747
http://dx.doi.org/10.3389/fimmu.2018.00525