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Naltrexone Reverses Ethanol Preference and Protein Kinase C Activation in Drosophila melanogaster

Alcohol use disorder (AUD) is a major health, social and economic problem for which there are few effective treatments. The opiate antagonist naltrexone is currently prescribed clinically with mixed success. We have used naltrexone in an established behavioral assay (CAFE) in Drosophila melanogaster...

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Detalles Bibliográficos
Autores principales: Koyyada, Rajeswari, Latchooman, Nilesh, Jonaitis, Julius, Ayoub, Samir S., Corcoran, Olivia, Casalotti, Stefano O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861182/
https://www.ncbi.nlm.nih.gov/pubmed/29593550
http://dx.doi.org/10.3389/fphys.2018.00175