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The Cytochrome P450-Mediated Metabolism Alternation of Four Effective Lignans From Schisandra chinensis in Carbon Tetrachloride-Intoxicated Rats and Patients With Advanced Hepatocellular Carcinoma

It is highly valuable to study the pharmacokinetics of herbal components under the pathological condition of liver dysfunction for safe and rational use of herbal medicines. In this study, the pharmacokinetic profiles of four effective lignans from Schisandra chinensis (SC), schisandrin, schisanther...

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Detalles Bibliográficos
Autores principales: Wu, Rongrong, Xiao, Zhiyong, Zhang, Xiaorui, Liu, Feng, Zhou, Wenxia, Zhang, Yongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861220/
https://www.ncbi.nlm.nih.gov/pubmed/29593545
http://dx.doi.org/10.3389/fphar.2018.00229