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Next generation sequencing of HIV-1 protease in the PIVOT trial of protease inhibitor monotherapy

BACKGROUND: The PIVOT trial examined whether patients with suppressed viral load on combination antiretroviral therapy could be safely switched long-term to ritonavir-boosted protease inhibitor (PI) monotherapy. The main trial publication reported that only one of 296 patients allocated to PI monoth...

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Detalles Bibliográficos
Autores principales: Dunn, David T., Stöhr, Wolfgang, Arenas-Pinto, Alejandro, Tostevin, Anna, Mbisa, Jean L., Paton, Nicholas I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861306/
https://www.ncbi.nlm.nih.gov/pubmed/29428459
http://dx.doi.org/10.1016/j.jcv.2018.02.003