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Human hepatocyte depletion in the presence of HIV-1 infection in dual reconstituted humanized mice

Human immunodeficiency virus type 1 (HIV-1) infection impairs liver function, and liver diseases have become a leading cause of morbidity in infected patients. The immunopathology of liver damage caused by HIV-1 remains unclear. We used chimeric mice dually reconstituted with a human immune system a...

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Detalles Bibliográficos
Autores principales: Dagur, Raghubendra Singh, Wang, Weimin, Cheng, Yan, Makarov, Edward, Ganesan, Murali, Suemizu, Hiroshi, Gebhart, Catherine L., Gorantla, Santhi, Osna, Natalia, Poluektova, Larisa Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861361/
https://www.ncbi.nlm.nih.gov/pubmed/29361613
http://dx.doi.org/10.1242/bio.029785