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Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice

Site-1 protease (S1P) is a proprotein convertase with essential functions in the conversion of precursor proteins to their active form. In earlier studies, we demonstrated that S1P ablation in the chondrocyte lineage results in a drastic reduction in endochondral bone formation. To investigate the m...

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Detalles Bibliográficos
Autores principales: Patra, Debabrata, DeLassus, Elizabeth, Mueller, Jennifer, Abou-Ezzi, Grazia, Sandell, Linda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861364/
https://www.ncbi.nlm.nih.gov/pubmed/29437042
http://dx.doi.org/10.1242/bio.032094