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RAD51 and RTEL1 compensate telomere loss in the absence of telomerase

Replicative erosion of telomeres is naturally compensated by telomerase and studies in yeast and vertebrates show that homologous recombination can compensate for the absence of telomerase. We show that RAD51 protein, which catalyzes the key strand-invasion step of homologous recombination, is local...

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Detalles Bibliográficos
Autores principales: Olivier, Margaux, Charbonnel, Cyril, Amiard, Simon, White, Charles I, Gallego, Maria E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861403/
https://www.ncbi.nlm.nih.gov/pubmed/29346668
http://dx.doi.org/10.1093/nar/gkx1322