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RAD51 and RTEL1 compensate telomere loss in the absence of telomerase
Replicative erosion of telomeres is naturally compensated by telomerase and studies in yeast and vertebrates show that homologous recombination can compensate for the absence of telomerase. We show that RAD51 protein, which catalyzes the key strand-invasion step of homologous recombination, is local...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861403/ https://www.ncbi.nlm.nih.gov/pubmed/29346668 http://dx.doi.org/10.1093/nar/gkx1322 |