DNA-binding landscape of IRF3, IRF5 and IRF7 dimers: implications for dimer-specific gene regulation

Transcription factors IRF3, IRF5 and IRF7 (IRF3/5/7) have overlapping, yet distinct, roles in the mammalian response to pathogens. To examine the role that DNA-binding specificity plays in delineating IRF3/5/7-specific gene regulation we used protein-binding microarrays (PBMs) to characterize the DN...

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Detalles Bibliográficos
Autores principales: Andrilenas, Kellen K, Ramlall, Vijendra, Kurland, Jesse, Leung, Brandon, Harbaugh, Allen G, Siggers, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861432/
https://www.ncbi.nlm.nih.gov/pubmed/29361124
http://dx.doi.org/10.1093/nar/gky002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861432/
https://www.ncbi.nlm.nih.gov/pubmed/29361124
http://dx.doi.org/10.1093/nar/gky002

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