Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder

Defects in neurogenesis alter brain circuit formations and may lead to neurodevelopmental disorders such as autism and schizophrenia. Histone H2A.z, a variant of histone H2A, plays critical roles in chromatin structure and epigenetic regulation, but its function and mechanism in brain development re...

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Detalles Bibliográficos
Autores principales: Shen, Tianjin, Ji, Fen, Wang, Yuanyuan, Lei, Xuepei, Zhang, Dongming, Jiao, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861433/
https://www.ncbi.nlm.nih.gov/pubmed/29294103
http://dx.doi.org/10.1093/nar/gkx1295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861433/
https://www.ncbi.nlm.nih.gov/pubmed/29294103
http://dx.doi.org/10.1093/nar/gkx1295

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