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Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder
Defects in neurogenesis alter brain circuit formations and may lead to neurodevelopmental disorders such as autism and schizophrenia. Histone H2A.z, a variant of histone H2A, plays critical roles in chromatin structure and epigenetic regulation, but its function and mechanism in brain development re...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861433/ https://www.ncbi.nlm.nih.gov/pubmed/29294103 http://dx.doi.org/10.1093/nar/gkx1295 |