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Structural characterization of the Asf1–Rtt109 interaction and its role in histone acetylation

Acetylation of histone H3 at lysine-56 by the histone acetyltransferase Rtt109 in lower eukaryotes is important for maintaining genomic integrity and is required for C. albicans pathogenicity. Rtt109 is activated by association with two different histone chaperones, Vps75 and Asf1, through an unknow...

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Detalles Bibliográficos
Autores principales: Lercher, Lukas, Danilenko, Nataliya, Kirkpatrick, John, Carlomagno, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861439/
https://www.ncbi.nlm.nih.gov/pubmed/29300933
http://dx.doi.org/10.1093/nar/gkx1283