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Multimode drug inducible CRISPR/Cas9 devices for transcriptional activation and genome editing

Precise investigation and manipulation of dynamic biological processes often requires molecular modulation in a controlled inducible manner. The clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR associated protein 9 (Cas9) has emerged as a versatile tool for targeted gene e...

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Detalles Bibliográficos
Autores principales: Lu, Jia, Zhao, Chen, Zhao, Yingze, Zhang, Jingfang, Zhang, Yue, Chen, Li, Han, Qiyuan, Ying, Yue, Peng, Shuai, Ai, Runna, Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861443/
https://www.ncbi.nlm.nih.gov/pubmed/29237052
http://dx.doi.org/10.1093/nar/gkx1222