The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts

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Numerous mammalian proto-oncogene and other growth-regulatory transcripts are upregulated in malignancy due to abnormal mRNA stabilization. In hepatoma cells expressing a hepatitis C virus (HCV) subgenomic replicon, we found that the viral nonstructural protein 5A (NS5A), a protein known to bind to...

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Detalles Bibliográficos
Autores principales: Guo, Liang, Sharma, Suresh D, Debes, Jose D, Beisang, Daniel, Rattenbacher, Bernd, Louis, Irina Vlasova-St, Wiesner, Darin L, Cameron, Craig E, Bohjanen, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861452/
https://www.ncbi.nlm.nih.gov/pubmed/29385522
http://dx.doi.org/10.1093/nar/gky061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861452/
https://www.ncbi.nlm.nih.gov/pubmed/29385522
http://dx.doi.org/10.1093/nar/gky061

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