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Addition of the Aβ42/40 ratio to the cerebrospinal fluid biomarker profile increases the predictive value for underlying Alzheimer’s disease dementia in mild cognitive impairment

BACKGROUND: Cerebrospinal fluid (CSF) biomarkers have been used to increase the evidence of underlying Alzheimer’s disease (AD) pathology in mild cognitive impairment (MCI). However, CSF biomarker-based classification often results in conflicting profiles with controversial prognostic value. Normali...

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Detalles Bibliográficos
Autores principales: Baldeiras, Inês, Santana, Isabel, Leitão, Maria João, Gens, Helena, Pascoal, Rui, Tábuas-Pereira, Miguel, Beato-Coelho, José, Duro, Diana, Almeida, Maria Rosário, Oliveira, Catarina Resende
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861634/
https://www.ncbi.nlm.nih.gov/pubmed/29558986
http://dx.doi.org/10.1186/s13195-018-0362-2