UDiTaS™, a genome editing detection method for indels and genome rearrangements

BACKGROUND: Understanding the diversity of repair outcomes after introducing a genomic cut is essential for realizing the therapeutic potential of genomic editing technologies. Targeted PCR amplification combined with Next Generation Sequencing (NGS) or enzymatic digestion, while broadly used in the...

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Detalles Bibliográficos
Autores principales: Giannoukos, Georgia, Ciulla, Dawn M., Marco, Eugenio, Abdulkerim, Hayat S., Barrera, Luis A., Bothmer, Anne, Dhanapal, Vidya, Gloskowski, Sebastian W., Jayaram, Hariharan, Maeder, Morgan L., Skor, Maxwell N., Wang, Tongyao, Myer, Vic E., Wilson, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861650/
https://www.ncbi.nlm.nih.gov/pubmed/29562890
http://dx.doi.org/10.1186/s12864-018-4561-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861650/
https://www.ncbi.nlm.nih.gov/pubmed/29562890
http://dx.doi.org/10.1186/s12864-018-4561-9

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