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Inhibitory Effects of Plumbagin on Retinal Pigment Epithelial Cell Epithelial-Mesenchymal Transition In Vitro and In Vivo

BACKGROUND: This study aimed to explore the effects of plumbagin (PLB) on epithelial-to-mesenchymal transition in retinal pigment epithelial (RPE) cells and in proliferative vitreoretinopathy (PVR) rabbit models. MATERIAL/METHODS: Rabbit RPE cells were exposed to various concentrations (0, 5, 15, an...

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Detalles Bibliográficos
Autores principales: Chen, Haitin, Wang, Huifang, An, Jianbin, Shang, Qingli, Ma, Jingxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861765/
https://www.ncbi.nlm.nih.gov/pubmed/29532788
http://dx.doi.org/10.12659/MSM.906265