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A Simple and Rapid Gene Disruption Strategy in Mycobacterium abscessus: On the Design and Application of Glycopeptidolipid Mutants

Little is known about the disease-causing genetic determinants that are used by Mycobacterium abscessus, increasingly acknowledged as an important emerging pathogen, notably in cystic fibrosis. The presence or absence of surface exposed glycopeptidolipids (GPL) conditions the smooth (S) or rough (R)...

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Detalles Bibliográficos
Autores principales: Viljoen, Albertus, Gutiérrez, Ana Victoria, Dupont, Christian, Ghigo, Eric, Kremer, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861769/
https://www.ncbi.nlm.nih.gov/pubmed/29594066
http://dx.doi.org/10.3389/fcimb.2018.00069