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The establishment of surrogates and correlates of protection: Useful tools for the licensure of effective influenza vaccines?

The search for a test that can predict vaccine efficacy is an important part of any vaccine development program. Although regulators hesitate to acknowledge any test as a true ‘correlate of protection’, there are many precedents for defining ‘surrogate’ assays. Surrogates can be powerful tools for v...

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Detalles Bibliográficos
Autores principales: Ward, Brian J., Pillet, Stephane, Charland, Nathalie, Trepanier, Sonia, Couillard, Julie, Landry, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861778/
https://www.ncbi.nlm.nih.gov/pubmed/29252098
http://dx.doi.org/10.1080/21645515.2017.1413518