Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice

Osteoarthritis (OA) is the leading form of arthritis in the elderly, causing pain, disability, and immobility. OA has been associated with accumulation of senescent cells in or near joints. However, evidence for a causal link between OA and cellular senescence is lacking. Here, we present a novel se...

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Detalles Bibliográficos
Autores principales: Xu, Ming, Bradley, Elizabeth W., Weivoda, Megan M., Hwang, Soyun M., Pirtskhalava, Tamar, Decklever, Teresa, Curran, Geoffry L., Ogrodnik, Mikolaj, Jurk, Diana, Johnson, Kurt O., Lowe, Val, Tchkonia, Tamar, Westendorf, Jennifer J., Kirkland, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861939/
https://www.ncbi.nlm.nih.gov/pubmed/27516624
http://dx.doi.org/10.1093/gerona/glw154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861939/
https://www.ncbi.nlm.nih.gov/pubmed/27516624
http://dx.doi.org/10.1093/gerona/glw154

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