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Life-span Extension With Reduced Somatotrophic Signaling: Moderation of Aging Effect by Signal Type, Sex, and Experimental Cohort

Reduced somatotrophic signaling through the growth hormone (GH) and insulin-like growth factor pathways (IGF1) can delay aging, although the degree of life-extension varies markedly across studies. By collating data from previous studies and using meta-analysis, we tested whether factors including s...

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Detalles Bibliográficos
Autores principales: Garratt, Michael, Nakagawa, Shinichi, Simons, Mirre J P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861954/
https://www.ncbi.nlm.nih.gov/pubmed/28207064
http://dx.doi.org/10.1093/gerona/glx010