APC Moonlights to Prevent Wnt Signalosome Assembly

The scaffold protein APC has a well-known function in ensuring β-catenin destruction. In this issue of Developmental Cell, Saito-Diaz et al. (2018) uncover another role for APC in Wnt signaling: to prevent clathrin-dependent signalosome formation in the absence of ligand.

Detalles Bibliográficos
Autores principales: McGough, Ian John, Vincent, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861992/
https://www.ncbi.nlm.nih.gov/pubmed/29533767
http://dx.doi.org/10.1016/j.devcel.2018.02.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861992/
https://www.ncbi.nlm.nih.gov/pubmed/29533767
http://dx.doi.org/10.1016/j.devcel.2018.02.018

Ejemplares similares