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APC Moonlights to Prevent Wnt Signalosome Assembly
The scaffold protein APC has a well-known function in ensuring β-catenin destruction. In this issue of Developmental Cell, Saito-Diaz et al. (2018) uncover another role for APC in Wnt signaling: to prevent clathrin-dependent signalosome formation in the absence of ligand.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861992/ https://www.ncbi.nlm.nih.gov/pubmed/29533767 http://dx.doi.org/10.1016/j.devcel.2018.02.018 |
| _version_ | 1783308156477112320 |
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| author | McGough, Ian John Vincent, Jean-Paul |
| author_facet | McGough, Ian John Vincent, Jean-Paul |
| author_sort | McGough, Ian John |
| collection | PubMed |
| description | The scaffold protein APC has a well-known function in ensuring β-catenin destruction. In this issue of Developmental Cell, Saito-Diaz et al. (2018) uncover another role for APC in Wnt signaling: to prevent clathrin-dependent signalosome formation in the absence of ligand. |
| format | Online Article Text |
| id | pubmed-5861992 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | Cell Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-58619922018-03-22 APC Moonlights to Prevent Wnt Signalosome Assembly McGough, Ian John Vincent, Jean-Paul Dev Cell Article The scaffold protein APC has a well-known function in ensuring β-catenin destruction. In this issue of Developmental Cell, Saito-Diaz et al. (2018) uncover another role for APC in Wnt signaling: to prevent clathrin-dependent signalosome formation in the absence of ligand. Cell Press 2018-03-12 /pmc/articles/PMC5861992/ /pubmed/29533767 http://dx.doi.org/10.1016/j.devcel.2018.02.018 Text en © 2018 The Francis Crick Institute http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article McGough, Ian John Vincent, Jean-Paul APC Moonlights to Prevent Wnt Signalosome Assembly |
| title | APC Moonlights to Prevent Wnt Signalosome Assembly |
| title_full | APC Moonlights to Prevent Wnt Signalosome Assembly |
| title_fullStr | APC Moonlights to Prevent Wnt Signalosome Assembly |
| title_full_unstemmed | APC Moonlights to Prevent Wnt Signalosome Assembly |
| title_short | APC Moonlights to Prevent Wnt Signalosome Assembly |
| title_sort | apc moonlights to prevent wnt signalosome assembly |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861992/ https://www.ncbi.nlm.nih.gov/pubmed/29533767 http://dx.doi.org/10.1016/j.devcel.2018.02.018 |
| work_keys_str_mv | AT mcgoughianjohn apcmoonlightstopreventwntsignalosomeassembly AT vincentjeanpaul apcmoonlightstopreventwntsignalosomeassembly |