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The senescent bystander effect is caused by ROS-activated NF-κB signalling

Cell senescence is an important driver of the ageing process. The accumulation of senescent cells in tissues is accelerated by stress signals from senescent cells that induce DNA damage and ultimately senescence in bystander cells. We examine here the interplay of senescence-associated mitochondrial...

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Detalles Bibliográficos
Autores principales: Nelson, Glyn, Kucheryavenko, Olena, Wordsworth, James, von Zglinicki, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861994/
https://www.ncbi.nlm.nih.gov/pubmed/28837845
http://dx.doi.org/10.1016/j.mad.2017.08.005