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The senescent bystander effect is caused by ROS-activated NF-κB signalling
Cell senescence is an important driver of the ageing process. The accumulation of senescent cells in tissues is accelerated by stress signals from senescent cells that induce DNA damage and ultimately senescence in bystander cells. We examine here the interplay of senescence-associated mitochondrial...
Autores principales: | Nelson, Glyn, Kucheryavenko, Olena, Wordsworth, James, von Zglinicki, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ireland
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861994/ https://www.ncbi.nlm.nih.gov/pubmed/28837845 http://dx.doi.org/10.1016/j.mad.2017.08.005 |
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