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Acute myeloid leukemia xenograft success prediction: Saving time

Xenograft assay allows functional analysis of leukemia-initiating cells of acute myeloid leukemia primary samples. However, 40% of samples derived from patients with better outcomes fail to engraft in immunodeficient mouse recipients when conventional protocols are followed. At diagnosis, the engraf...

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Detalles Bibliográficos
Autores principales: Griessinger, Emmanuel, Vargaftig, Jacques, Horswell, Stuart, Taussig, David C., Gribben, John, Bonnet, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861995/
https://www.ncbi.nlm.nih.gov/pubmed/29253573
http://dx.doi.org/10.1016/j.exphem.2017.12.002