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Tri-block polymer with interfacial layer formation ability and its use in maintaining supersaturated drug solution after dissolution of solid dispersions

BACKGROUND: Maintaining a supersaturated drug solution after the dissolution of the solid dispersions of water insoluble drugs continues to be a great challenge and is important to the oral bioavailability enhancement of hardly soluble drugs. METHODS: Nimodipine solid dispersions were prepared by ho...

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Detalles Bibliográficos
Autores principales: Fu, Ji-Jun, Liu, Cheng-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862016/
https://www.ncbi.nlm.nih.gov/pubmed/29588588
http://dx.doi.org/10.2147/IJN.S152415