Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice

Progress in gene editing research has been accelerated by utilizing engineered nucleases in combination with induced pluripotent stem cell (iPSC) technology. Here, we report transcription activator-like effector nuclease (TALEN)-mediated reincorporation of Arg1 exons 7 and 8 in iPSCs derived from ar...

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Detalles Bibliográficos
Autores principales: Sin, Yuan Yan, Ballantyne, Laurel L., Richmond, Christopher R., Funk, Colin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862027/
https://www.ncbi.nlm.nih.gov/pubmed/29499927
http://dx.doi.org/10.1016/j.omtn.2017.11.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862027/
https://www.ncbi.nlm.nih.gov/pubmed/29499927
http://dx.doi.org/10.1016/j.omtn.2017.11.012

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