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Targeted Delivery of Auristatin-Modified Toxins to Pancreatic Cancer Using Aptamers
Pancreatic cancer is one of the most lethal malignancies. Treatment with the first-line agent, gemcitabine, is often unsuccessful because it, like other traditional chemotherapeutic agents, is non-specific, resulting in off-target effects that necessitate administration of subcurative doses. Alterna...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society of Gene & Cell Therapy
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862029/ https://www.ncbi.nlm.nih.gov/pubmed/29499935 http://dx.doi.org/10.1016/j.omtn.2017.11.013 |